The third iteration, that became the original Mary D. Bradford High School building, was built in 1924 and is located at Sheridan Road and 57th Street.

In 1975, the Kenosha Unified School Board purchased the former University of Wisconsin-Extension Center located at 39th Avenue and Washington Road, which had been built in 1961, with an addition in 1965.

A major addition was constructed to the building in 1979 which included all of the components of a contemporary high school.

Since Bradford High School moved to the Washington Road location, two soccer fields have been added north of the school, a varsity baseball stadium has been created to the northeast, and three practice American football fields have been created north of the ravine.

On September 1, 2020, President Donald Trump visited the school following a period of violence and unrest in the city.