[1] McChesney was born to Robert Fuller and Karen Rasmussen on October 20, 1922,[2] in Wichita, Kansas and grew up in Stockton, California after moving there at age two with her family.
She started a ceramics business of her own, along with her partner Avrum "Bill" Rubenstein: "Two Fish Pottery".
[3] Through her association with The Artists' Guild Gallery, she became acquainted with a wide variety of her contemporary artists, including Hassel Smith, Ed Corbett, Emmy Lou Packard, Robert P. McChesney, George Goya, John Hultbert, Clyfford Still, and Ad Reinhardt.
[5] They moved to Sonoma Mountain in Sonoma County near Petaluma, California in 1952, after living in Mexico for a year, and lived and worked there through Robert McChesney's death in 2008, after which Mary remained there, continuing to work, until the late 2010s.
[6][3] She experimented with different sculpture formats, including wood and stone, before developing the cement mixed with vermiculite that she used for the majority of her work.