[4] She became the only female member of the senior faculty in the chemistry department,[1] becoming the first woman to attain the rank of assistant professor at Columbia.

[6] In 1960 she received the Garvan Medal from the American Chemical Society, an honor awarded annually to a US female chemist.

She attempted to find a more pure form of amylase and she was able to develop a method for isolating crystalline pancreatic enzymes.

[8][9] In 1960, Caldwell was awarded the Garvan Medal by the American Chemistry Society for her research on amylase.

The Garvan Medal specifically recognizes women who have made a significant contribution to the field of Chemistry.

Caldwell developed a method to isolate crystalline pancreatic enzymes that is now used by laboratories all throughout America and Europe.