Mary Lou Marzian (born September 16, 1954) is an American politician and a Democratic member of the Kentucky House of Representatives, representing district 41 since January 2025.

[1] Marzian was first elected in a January 1994 special election following the resignation of incumbent Mike Ward.

[2] She retired from the house in 2022 after being redistricted into the 41st district with Josie Raymond.

She ran again for the house in 2024, winning the 41st district.

Marzian earned her associate degree from Jefferson Community College (now Jefferson Community and Technical College) and her BSN from the University of Louisville.