The Mary McLeod Bethune Home is a historic house on the campus of Bethune-Cookman University in Daytona Beach, Florida.

Built in the early-1900s, it was home to Mary McLeod Bethune (1875–1955), a prominent African-American educator and civil rights leader, from 1913 until her death.

The Mary McLeod Bethune Home is located on the northeast side of the Bethune-Cookman campus, west of Doctor Martin Luther King Jr. Boulevard.

[4] Bethune, an African-American born to formerly enslaved parents, achieved nationwide notice for her success in establishing the school, and went on to play an important role in the advance of education and civil rights, particularly in the years between World War I and World War II.

[3] The Mary McLeod Bethune Foundation was founded in 1953 to preserve her legacy, and is now responsible for the house's maintenance.