Mary Rose Columba Adams (21 March 1832 — 30 December 1891), born Sophia Charlotte Louisa Adams, was an English Roman Catholic Dominican prioress, recognized as a founder of St Dominic's Priory and the Church of Perpetual Adoration in North Adelaide, Australia.

In the summer of 1883, Mother Rose Columba left that work to lead a group of eight overseas to Australia, where Dominican sisters were called to nurse.

In Adelaide, the sisters opened a school, embroidered, painted, and cared for the sick, while Mother Rose Columba worked to establish a spiritual component to the community.

[2][3] Mother Rose Columba Adams died in 1891, aged 59, from kidney failure, at the convent she founded in North Adelaide.

[4] The girls' school she and her group founded in North Adelaide remains in operation as St Dominic's Priory College.