The following year, she attended the Northwestern University Woman's Medical School in Chicago, Illinois, from which she was graduated.

Her duties were so arduous, the lack of nurses making it necessary for her to supply that position sometimes, that, after four months' service, she resigned and returned home for rest.

[1] While on a visit to her brother in Dorchester, Nebraska, her practice became so extensive as to cause her to settle there, where she gradually overcame opposition among physicians and people to women practitioners.

She was a contributor to the Omaha, Nebraska Clinic and other medical journals, and was State superintendent of hygiene and heredity for the Woman's Christian Temperance Union (WCTU), county and local.

[1] Associated with all progressive movements, Butin worked to end the prejudice against woman in the field of medical science.

[5] Butin was active in the woman's suffrage movement with Carrie Chapman Catt and Susan B.