MD 755 begins at an entrance to the Edgewood Area of Aberdeen Proving Ground; the highway continues south into the military installation as Wise Road.

The state highway continues north through residential subdivisions until an acute intersection with MD 24 (Emmorton Road).

Edgewood Road continues north as a two-lane county highway that crosses Winters Run, has a one-lane underpass of CSX's Philadelphia Subdivision railroad line, and intersects MD 7 before veering northeast to another intersection with MD 24 just south of Interstate 95 (I-95).

[6] MD 408 received an underpass of the Baltimore and Ohio Railroad (now CSX) and approaches to the grade separation in 1939.

[12] MD 755 achieved its present length around 1991 when the portion of Edgewood Road north of US 40 was transferred to county maintenance.