As Pawtucket Boulevard, Route 113 follows the Merrimack into the city of Lowell.

Once in Lowell, Route 113 acts as a parkway along the north bank of the river, intersecting the Rourke Bridge and the O'Donnell Bridge near the Pawtucket Falls before splitting from the parkway, which turns into the VFW Highway.

It crosses the Beaver Brook before intersecting with Route 38 near the town center.

From there, Route 113 continues through a rural section of Dracut into Methuen and Essex County.

In Haverhill, Routes 113 and 110 follow the north bank of the Merrimack, and meet I-495 at Exit 107.

It then joins Route 97 at Ginty Boulevard, running concurrently through the eastern end of town, passing Holy Family Hospital at Merrimack Valley, Riverside Park, and Trinity Stadium, locally known for being the site of an exhibition featuring Babe Ruth.

[2] In late 2011, through traffic just east of the bridge was rerouted to curve away from the Merrimack River before rejoining the original right of way.