Route 286 is a 3.7-mile-long (6.0 km) east–west state highway in Salisbury, Massachusetts and Seabrook, New Hampshire.

Route 286 then continues to its eastern terminus with New Hampshire Route 1A (Ocean Boulevard), which runs north–south along the Atlantic shore, approximately 160 feet (49 m) north of the Massachusetts/New Hampshire state line.

In 1984, plans to connect I-84 along the present day I-384/US 6 corridor from Hartford to Providence were scuttled for environmental reasons.

The Massachusetts State Route has kept the 286 number, and by extension the New Hampshire road has as well.

Today, I-86 is the former Southern Tier Expressway/NY Route 17 in New York State as that road is upgraded to Interstate Highway standards.