It then heads into Hubbardston, crossing Route 62 and passing through the center of town before bending more northeasterly into the city of Gardner.

Route 68 heads into Templeton before joining U.S. Route 202 for a wrong-way concurrency for 1.4 miles (2.3 km) through the Baldwinville section of town, before turning northwestward again.

The route passes through the far northern portion of neighboring Phillipston before entering Royalston.

In Royalston, the route winds slowly through the woods and hills, crossing the Millers River and heading northward through the center of the town.

It finally ends at Route 32, just two miles south of the New Hampshire state line.