This resulted in a hotbed of endemism in la Hotte's bird, plant, and reptile communities.

The Occidental la Hotte is relatively remote and is one of the most biologically diverse and significant areas of all of Hispaniola.

Conservation International recognizes the region, in which 13 of Hispaniola's most critically endangered species (all amphibians) occur, as one of the most conservation-urgent in the world.

The Hispaniolan trogon, Haiti's national bird, has a recognized presence in the region, as well as wintering Bicknell's thrushes.

The two protected areas with sustainable use of natural resources are: Jeremie - Abricot and Barcaderes Caymites.