Mast cell stabilizer

Mast cell stabilizers are medications used to prevent or treat certain allergic disorders.

One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels.

Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate.

[2] Finally, in oral form, they are used to treat the rare condition of mastocytosis.

[3][4] Mast cell stabilizer medications include: The following substances are studied on their potential mast cell stabilizing effects, but the current results are inconclusive: