Matabeleland South sits on the edge of the Kalahari Desert, giving it an arid climate not hospitable to agriculture.

Towns and villages in Matabeleland South include Antelope Mine, Beitbridge, Brunapeg, Colleen Bawn, Esigodini, Filabusi,Fort Rixon, Gwai, Gwanda, Kafusi, Kezi, Madlambudzi, Makhado, Maphisa, Masendu, Ndolwane, Plumtree, Shangani, Stanmore, Tshitshi, Bulu, West Nicholson, and Zezani.

The current Minister of State for Matabeleland South Province is Abednico Ncube, a ZANU–PF member who was appointed by President Emmerson Mnangagwa in December 2017.

Matabeleland South Province is divided into seven districts: Beitbridge, Bulilima, Gwanda, Insiza, Mangwe, Matobo, and Umzingwane.

[7] Senators are not directly elected by voters, but are instead selected by party lists via a proportional representation system.

Fast forward in 2023 now CCC and still under Nelson Chamisa the opposition made serious in roads and managed to wrestle 4 seats that is Mangwe- Matobo, Gwanda North ,Mangwe and Beitbridge west.