[1] Kenmore House is a two storeyed brick building erected c. 1894 as a residence for John Ferguson on the Athelstane Range overlooking Rockhampton.

The house contained a ballroom tiled with locally quarried black and white marble and a reception hall on the first floor.

In 1894, after the death of architect Flint, tenders were called by Eaton and Bates for the erection of two sets of grand entrance gates.

[1] Kenmore House, located on a northeast sloping site on the Athelstane Range, is a two-storeyed residence and administration centre built of Flemish bond brickwork with rendered detailing and a hipped corrugated iron roof.

The asymmetrically massed building shows Classical influences in its design, including a Corinthian columned portico on the north with a tower above, large cornice, arcaded loggias, quoining, pilasters, projecting bays, bracketed eaves and rendered balustrade.

The single-storeyed former hospital reception area is attached as a lean-to on the northeast with a brick hydraulic lift shaft standing proud of the building's facade and a glass walkway linked to the first floor.

[1] Internally, the north entrance leads into a large, columned central hall containing a carved cedar staircase with a twin return and a large stained glass window, ornate plaster ceilings, marble floors with decorative tiled borders and converted gas lanterns.

The two-storeyed timber, former canteen building is linked to this level at the southwest via an enclosed verandah above a rear service entrance.

[1] The north grounds, bounded by the recent hospital extensions to the northeast and the two-storeyed brick medical centre to the west, include a large Tamarind Tree to the northwest surrounded by bitumen carpark.

It is also significant for its association with the longstanding role of the Sisters of Mercy and their Mater Misericordiae Hospitals in the state's health system.

It has a special association with the community of the Sisters of Mercy and the Mater Misericordiae Hospital since 1915, and with Rockhampton as a historic landmark for the city and district.

It has a special association with the life and work of people of importance in Queensland's history, in particular John Ferguson, builder, businessman, politician and separationist; Rockhampton architect James Flint; and the Sisters of Mercy.