Mater Spei College is a government-aided Catholic secondary school located in Francistown, Botswana.

[6] The school received considerable financial support from the Botswana government, which made significant capital investment in building projects at the school to support the institution's expansion in its early years.

[8] The school has facilities including double-storey classrooms, a multi-purpose hall and a networked (Internet-connected) library.

[9] In 2018 the school had the second highest academic results in Botswana for the country's BGCE examinations.

[10] Mater Spei College has twelve subject departments, which includes: A 2016 study found that this school was ahead of others in information and communications technology because of equipment and software provided by a local mining company.