Located on the left bank of the Indus River, Matiari became an independent district on 30 May 2004 during the military regime of Pervez Musharraf, when Hyderabad was divided into four districts — Tando Allahyar, Matiari, Tando Mohammad Khan and Hyderabad.

People of Matiari would tell the bus conductor to stop at "Mat Wari Maai" (old woman's hut where she keeps earthen pot of water).

Pathan Village Jon Landhiyoon Kaka Nizamani Ji Wasi Station Thorra/Kheber Muhammad Shah Ajnani Rahu Arif Khatian Hothiani Borero Hussain Hingoro Old Ramzan Unar As of the 2023 census, Matiari district has 158,463 households and a population of 849,383.

[11] At the time of the 2023 census, 92.95% of the population spoke Sindhi, 2.66% Urdu, 1.33% Balochi and 1.31% Hindko as their first language.

At Khuda aabad, one can find the graves and the tombs of Mughal Empires era.

The main crops cultivated are cotton, banana, mango, wheat, onions and sugarcane.