It was relatively unsuccessful compared to its sibling, the Cosworth DFV powered Matra MS10 which Jackie Stewart drove to second place in the World Drivers' Championship.

The major problems were with the Matra Sports V12 engine, which was thirsty, underpowered, unreliable and prone to overheating.

Its best outing came at the 1968 Dutch Grand Prix where Beltoise finished second behind Stewart, and recorded the fastest lap.

In 1969, Matra set aside the V12 project, concentrating on the DFV-powered MS80.

(key) (results in bold indicate pole position; results in italics indicate fastest lap) 1 In the 1968 Constructors' Championship, Matra-Ford finished 3rd (45 points), Matra(-Matra) finished 9th (8 points)