Matsusaka (松阪市, Matsusaka-shi, Local dialect: Mattsaka or Massaka) is a city located in Mie Prefecture, Japan.

Matsusaka has a Humid subtropical climate (Köppen Cfa) characterized by warm summers and cool winters with light to no snowfall.

The city suffered only light damage in World War II, when an air raid killed four people on February 4, 1945.

On October 15, 1956, a major railway accident occurred at Rokken Station on the outskirts of the city, killing 42 people.

Matsusaka has a mayor-council form of government with a directly elected mayor and a unicameral city council of 28 members.

In terms of national politics, the city is part of Mie 1st district of the lower house of the Diet of Japan.