Matthew Thomas Belisle (beh-LYLE; born June 6, 1980) is an American former professional baseball pitcher.

He played in Major League Baseball (MLB) for the Cincinnati Reds, Colorado Rockies, St. Louis Cardinals, Washington Nationals, Minnesota Twins, and Cleveland Indians.

This was good enough to get Belisle a promotion to Single-A Advanced Myrtle Beach where he had a 3.43 ERA in 12 starts.

He spent all of 2002 and most of 2003 with the Double-A Greenville Braves before being traded to the Cincinnati Reds for veteran relief pitcher Kent Mercker as the PTBNL on August 14, 2003.

Belisle was assigned to Triple-A Louisville and was called up to the majors on September 7, 2003, making his debut that same day.

He was designated for assignment on May 25, he cleared waivers and was sent outright to Triple-A Colorado Springs Sky Sox the next day.

Belisle enjoyed the best season of his career with the Rockies in 2010, mostly as a setup pitcher, posting a 7–5 record, 2.93 ERA, 91 K in 92 innings of work.

In January 2011, he avoided salary arbitration with Colorado by signing a 1-year deal worth $2.35 million.

The Cardinals attempted to give him rest to alleviate the pain, but were unsuccessful, placing him on the disabled list on June 30.

Cubs pitcher Dan Haren hit teammate Matt Holliday in the back of the helmet.

Remarked Cubs manager Joe Maddon about Belisle hitting Rizzo, "I have no history with the Cardinals except I used to love them growing up.

[19] Belisle rejoined the Twins after signing a Major League contract with the team on June 11, 2018.

[20] In his second stint with the Twins, Belisle did not have a good outing, finishing the season with a 9.13 ERA in 25 appearances.