He is associate professor at the Western University of Health Sciences Department of Anatomy in California.

Wedel studies sauropods and the evolution of pneumatic bones in dinosaurs.

[2] He has authored papers naming Aquilops (2014), Brontomerus (2011),[3] and Sauroposeidon (2000).

[4] He has published research exploring how some dinosaurs achieved large sizes.

[6] Along with paleontologists Darren Naish and Mike P. Taylor, he founded the paleontology blog Sauropod Vertebrae Picture of the Week.