During his eight-year career in Major League Baseball (MLB), LeCroy had the dubious honor of being the active player with the most plate appearances without a stolen base.

Although challenged defensively behind the plate, averaging double-digit passed balls while throwing out less than 30 percent of potential base stealers, LeCroy put up superior power numbers in the minor leagues, hitting 101 home runs over five years in the Twins' system.

Despite bone spurs in his throwing knee, LeCroy was asked to fill in during a May 25, 2006, game against the Houston Astros when Washington's starting catcher Brian Schneider and backup Wiki Gonzalez were out with injuries.

He was replaced by utilityman Robert Fick in the middle of the seventh inning after the Astros stole seven bases and LeCroy committed two catching errors.

After the game, manager Frank Robinson shed tears during the press conference regarding his removal of Matt in the middle of the seventh inning, which is usually considered embarrassing.

[3] LeCroy was designated for assignment July 18, which he accepted, and spent the rest of the year playing for the New Orleans Zephyrs, then Washington's Triple–A affiliate team.

As a member of the Twins, LeCroy became one of the few major leaguers to pinch hit a walk-off grand slam in a win over the Toronto Blue Jays.