Senk has held the head coaching position at Stony Brook since prior to the 1991 season.

[7][8] Senk graduated from John Glenn High School in 1976 and attended Cortland State for college, where he played catcher.

[12] Nathan would become Senk's first recruit to reach the major leagues when he debuted for the San Francisco Giants as a pitcher in 1999.

Finishing the season at 52–15, Senk won the NCBWA National Coach of the Year award.

[17] The America East Conference suspended Senk for the first nine games of the 2022 season "in response to an incident that occurred during the 2021 season in which Coach Senk acted contrary to NCAA Baseball Rules and America East Bylaws governing conduct.