He appeared in an episode of The Streets of San Francisco and the movie The Candidate starring Robert Redford, which was filmed mostly in Berkeley, California.

He moved up the minor league baseball ranks over the next several years, working for various clubs in a number of different organizations, including the Syracuse Chiefs in 1995, and ending with the Triple–A Tucson Toros in 1996.

Starting in 2007, he also worked on Fox MLB telecasts of the Game of the Week, teaming with a variety of analysts on the network's #3 broadcast crew.

In 2016, Smoltz became lead game analyst at Fox and Buck Martinez became Vasgersian's new partner for the international broadcast of the World Series.

Vasgersian and Jim Kaat called Game 3 of the 2013 American League Division Series, also between the Detroit Tigers and the Oakland Athletics on October 7 as well.

In April 2022, MLB Network announced that Vasgersian would be the host of a new daytime sports betting show titled Pregame Spread.

[12] On January 23, 2018, it was announced that Vasgersian would become the new play-by-play voice for ESPN's Sunday Night Baseball beginning in the 2018 season, teaming with Alex Rodriguez, while continuing his role at MLB Network.

Vasgersian succeeded Dan Shulman, who moved to Sportsnet to call Toronto Blue Jays games for the 2019 season.

Daron Sutton was selected as the backup play-by-play announcer for games Vasgersian was unable to call due to his obligations to the national networks.

[16] Vasgersian returned to the Angels' booth for the 2022 season alongside Gubicza and new sideline reporter Erica Weston with more availability due to his October 2021 departure from ESPN.

As a result, Waltz was relieved of his secondary play-by-play duties and Angels Live host Patrick O'Neal called games in Vasgersian's future MLB Network-related absences.

Following the inaugural telecast in which he quipped, "I feel uncomfortable" after a suggestive shot of the cheerleaders, Vince McMahon personally demoted him and replaced him with wrestling announcer and former Atlanta Falcons play-by-play man Jim Ross.

Goldberg was working on Fox Sports Net's college football telecast on the night of UFC 56, so Vasgersian provided play-by-play alongside regular color commentator Joe Rogan.

He worked with Dave Campbell, Rex Hudler, Eric Karros, Steve Lyons, Harold Reynolds, Dan Plesac and Mark DeRosa.