Matthew Henry Cochrane (November 11, 1823 – August 12, 1903) was a Canadian industrialist, livestock breeder, and politician.

Born in Compton, Lower Canada, the eldest son of an Irish Anglican immigrant, James Cochrane, Cochrane was a cattle importer and breeder.

He was appointed to the Senate on the advice of John Alexander Macdonald in October 1872 representing the senatorial division of Wellington, Quebec.

He was one of the founders of the Eastern Townships Bank and Cochrane Ranch in Alberta was one of the largest in the British Empire.

This article about a Quebec Member of the Canadian Senate is a stub.