It originated from the Italian Jews and is popular in Israel, the United States, and the rest of the diaspora.

It is similar to the traditional Sephardic Jewish dish mina; though the fillings differ as mina is typically made with meat or a spinach and feta filling while matzo lasagna is made with sauce and cheese.

[2] During Passover, Jewish law prohibits the consumption of food items other than matzo that are made with wheat or other similar grains.

[3] Given these restrictions, some individuals will make lasagna by substituting matzo for traditional wheat pasta sheets.

[4][5] Matzo lasagna descended from a local Italian Jewish variant of a much older Sephardic culinary tradition of Passover pies, or casseroles, called minas.