Educated at Rangoon, Calcutta, London and Oxford, Gyee was called to the English bar by the Middle Temple in 1911.
A nationalist politician and a member of the moderate 21 Party, he was Minister of Education, Local Government and Public Health from 1923 to 1925.
In 1927, he was unseated from the legislation for corrupt practices by an electoral petition filed by U Ba Tin.
[2] From 1947 to 1948, Gyee served as Burmese High Commissioner, then ambassador to the United Kingdom.
He came out of retirement in 1960 as leader of the Buddhist Democratic Party, created to contest the 1960 Burmese general election.