From the age of six, Vachier-Lagrave competed in numerous sections of youth tournaments, winning the French Under-8 championship in 1997, U-10s in 1999, U-12s in 2000, U-16s in 2002, runner up in the U-18s in 2003 and won the U-20s in 2004 scoring 8/9.

Team results include: He played for the Évry Grand Roque chess club in 2008, 2009 and 2010.

In the European Chess Club Cup, he played with SV Mülheim Nord (in 2008), SOCAR Baku (in 2010), Clichy Échecs 92 (in 2013) and Obiettivo Risarcimento Padova (2014–2016).

[23] In addition to his strength in classical time controls, Vachier-Lagrave is very skilled at rapid and blitz chess.

He won the World Blitz Chess Championship 2021, and was the only player to defeat eventual winner Magnus Carlsen during the 2023 edition.