The name of the post office, established in 1915, honours R. I. Mayer, the first postmaster.

[1] On March 3, 2005, four officers serving with the Mayerthorpe and Whitecourt detachments of the Royal Canadian Mounted Police (RCMP) were killed in the Mayerthorpe tragedy.

In 2011, after three years of planning and fundraising, the new arena, now called the Mayerthorpe Exhibition Centre, was officially opened.

[8] In 2016, a string of suspicious fires in the area resulted in the destruction of a CN trestle bridge.

The team plays in the Mayerthorpe Exhibition Centre.