The total enrollment is about 330, with a 1:7 faculty/student ratio, an average class size of 15, has a 100% college acceptance rate and is 52% ethnically diverse.

Students take classes in eight different subject areas: English, Fine Arts, World Languages, Mathematics, Physical Education, Theology, Science, and Social Studies.

Originally known as the Marshallia mansion, Strub Hall, on Grand Avenue, was built in 1919.

It became Mayfield's Bellefontaine campus home in 1950, having been gifted by Dr. Charles H. Strub and his wife, Vera.

[3] Mayfield has also served as a filming location[4][5] for many TV shows and movies, such as Marvel’s Runaways, The Lost World: Jurassic Park , The Nutty Professor, All About Steve, and Legally Blonde.