It is a reggaeton and bachata fusion reminiscent of the single "Mayor Que Yo" (2005), in which Daddy Yankee and Wisin & Yandel participated, blending contemporary sounds with those found on that song, as well as "touches of merengue ripiao".

Commercially, it peaked at number one in the Dominican Republic, Mexico and Puerto Rico, at nine in Honduras, at 18 in El Salvador and at 29 on the US Billboard Hot Latin Songs chart.

"Mayor Que Usted" was written by Natti Natasha, Daddy Yankee, Wisin & Yandel, DJ Luian, Mambo Kingz's members Edgar Semper and Xavier Semper, Ovimael "OMB" Maldonado, Pusho, Kevin Galván, Kedin Maysonet, Wander Méndez, Rafael Salcedo and Pina Records' CEO Raphy Pina, who is Daddy Yankee's manager and Natti Natasha's husband.

[10][11][12] It also interpolates Wisin & Yandel's singles "Mírala Bien" (2005) and "Ahora Es" (2007) and Daddy Yankee's Talento de Barrio track "Come y Vete" (2008).

[20][21][22][23][24] Natti Natasha, Daddy Yankee and Wisin & Yandel performed the song live for the first time at the 19th Premios Juventud, held on July 21, 2022 at the José Miguel Agrelot Coliseum in San Juan, Puerto Rico.