The Mayor of Caloocan (Filipino: Punong Lungsod ng Kalookan) is the head of the local government of the city of Caloocan who elected to three-year terms.

The mayor is also the executive head and leads the city's departments in executing the city ordinances and improving public services.

The mayor holds office at both the Caloocan City Hall in Grace Park and at the Caloocan City Hall North in Camarin.

Along Malapitan is the incumbent mayor of the city since June 2022.

[1] Alejandro Fider (1963-1971) Oscar "Oca" Malapitan (1998-2001) Luis "Tito" Varela (2001-2004) Edgar "Egay" Erice (2010-2013) a Concurrently served as the District Chief of Caloocan, when it was part of the City of Greater Manila.