Maysville is an unincorporated community and a census-designated place (CDP) located in and governed by Chaffee County, Colorado, United States.

The population of the Maysville CDP was 173 at the United States Census 2020.

[3] The Salida post office (Zip Code 81201) serves the area.

[4] The Maysville CDP has an area of 7,957 acres (32.201 km2), including 8.4 acres (0.034 km2) of water.

[2] The United States Census Bureau initially defined the Maysville CDP for the United States Census 2010.