Maytown is an unincorporated community and census-designated place (CDP) in Lancaster County, Pennsylvania, United States.

[3] Maytown is noted as the birthplace of 19th-century politician Simon Cameron, who served in the Cabinet of President Abraham Lincoln.

Pennsylvania Route 743 (Maytown Road / South River Street) passes through the center of town, leading north 6 miles (10 km) to Elizabethtown and south 3 miles (5 km) to Marietta.

Lancaster, the county seat, is 15 miles (24 km) east of Maytown via Routes 441 and 23.

According to the U.S. Census Bureau, Maytown has a total area of 3.7 square miles (9.5 km2), of which 0.7 acres (2,999 m2), or 0.03%, are water.

[5] The community drains east and west to unnamed direct tributaries of the Susquehanna River.