He is the founder and CEO of Marketing Group for Advertising, Publishing and Distribution and the Dar al-Hadaf Newspaper Company, which he founded with Kuwaiti businessman Ahmed Al-Jarallah.

[3][4][5] He was named in the Panama Papers as the sole owner of First Kingston Investments Ltd., registered in the British Virgin Islands.

"[13] In 2021, the EU General Court dismissed an application by Mazen Al Tarazi to annul his inclusion in the Syria sanctions list.

[16] In March 2019, the Arab Times, owned by Al-Tarazi's business partner, Ahmed Al-Jarallah, published an article describing the allegations of money laundering against of Al-Tarazi as "concocted lies, as several bloggers have raised unfounded allegations in the past against notable personalities in the country, which clearly damaged their reputations and defamed their personalities".

[17] In December 2022, Al-Jarallah released a statement in his newspaper, the Arab Times announcing his "severance of any relationship with the so-called Mazen Al Tarazi".