Mazerolles (French pronunciation: [mazʁɔl]) is a commune in the Vienne department in the Nouvelle-Aquitaine region in western France.

Located on the Vienne river which separates Mazerolles and Lussac-les-Châteaux, the village is 35 km south-east of Poitiers.

Along the border of the river Vienne, a cenotaph of constable John Chandos was erected shortly after his death by the English authorities to commemorate the spot where he was killed by the spear of French knight Guillaume Boitel.

The cenotaph is still maintained and visible in a garden along the street Jean Chandos at a place called "Les Aubeniaux" .

At the end of the 19th century, the local society of history moved it from the banks of the Vienne because of recurrent flooding of this river.