[2] In 1937 she earned a master's degree in geography at Ohio State University, with a thesis titled "A Florida Phosphate Landscape.

[11] During World War II, Tyson headed a panel in Leon County, Florida, to monitor black businesses' compliance with wartime price regulations.

[14] Tyson was active in the Nashville branch of the American Association of University Women,[15][16] and in the sorority Zeta Phi Beta.

[19] Mazie Tyson married fellow professor Aurelius Southall Scott in 1928;[1] they ran a summer camp together in Ohio, and were on the faculty together at Bethune-Cookman College,[20] before they separated in the 1930s.

She retired from teaching in 1970,[21] and died from cancer and heart failure at a hospital on Saint Thomas, in the Virgin Islands, in 1975.