The interior has been substantially altered for use from its original religious functions, to house meeting spaces, a kitchen, classrooms, and storage.

The building was broken down and reconstructed near its present location, and from 1953 to 1968 it housed the growing Our Lady of Guadalupe congregation.

After construction of the modern church, the building was moved 450 feet (140 m) northwest, in order to accommodate the city's development of Mayfair Park.

[3] The building is historically significant for its association with labor leader and civil rights activist César Chávez.

The chapel became home to Chávez's chapter of the Community Service Organization, an important training ground for his later activism.