McGill–Toolen Catholic High School, founded as the McGill Institute and sometimes called "McT" for short, is a private co-educational high school operated by the educational system of the Roman Catholic Archdiocese of Mobile in Mobile, Alabama.

Bishop Toolen School for Girls was founded in 1928 by Bishop Thomas J. Toolen and was administered by the Sisters of Loretto until it merged with McGill Institute in 1972 to form the co-educational McGill–Toolen Catholic High School.

[3] In December 2007, the Mobile Register reported that supporters of the school raised $10.3 million to renovate the campus and add a new science building and student center.

The Yellow Jackets repeated in 2007 as the 6A Region 1 champs with an undefeated regular season record of 10–0.

In October 2007, the school announced the construction of a football stadium at the Archbishop Lipscomb Sports Complex.

Established in 1896, The McGill-Toolen High School Band is one of Alabama's oldest musical organizations.

On April 23, 2016, the McGill–Toolen Catholic High School Band traveled to New York City and made their Carnegie Hall premier.