Venado Tuerto (Spanish pronunciation: [beˈnaðo ˈtweɾto]) (Spanish for One Eyed Deer) is a city in the south-west of the province of Santa Fe, Argentina, 322 km from the provincial capital.

Venado Tuerto was founded on April 26, 1884 by Eduardo Casey, born in Lobos, Buenos Aires, in 1847.

Casey bought a large extension of land from where the natives had been recently expelled, to be employed for farming and horse breeding.

The name of the town literally means one-eyed deer, and its origin is unknown, though several folk legends circulate around it.

In any case, it was not considered tasteful by some, and on several occasions a change was formally requested, mainly to 'Ciudad Casey' ('Casey City'), though never carried out.