The episode follows Peter as he saves the life of a fast-food restaurant owner who gives him a lifetime supply of free hamburgers as a reward.
After eating 30 hamburgers in a row, Peter suffers a massive stroke and tries to take revenge on the restaurant.
This is one of the episodes that did not have show creator Seth MacFarlane's work in post-production because he was participating in the Writers Guild of America strike.
Recurring voice actors Alex Breckenridge, Phil LaMarr, Ralph Garman, Mark Hentemann, Danny Smith, Alec Sulkin, Lisa Wilhoit, and John Viener also made appearances.
At the grand re-opening, Peter drowns his sense of loss with 30 hamburgers, causing a stroke that paralyzes the left half of his body.
Unhappy about the pace of his recovery, Peter walks into a stem cell research center; he is cured of his stroke damage in only five minutes.
Peter loses the trial because the company has more lawyers, he offered the judge a cheap bribe, and because he has no evidence that McBurgertown was at fault.
Peter and Brian befriend a bull that is genetically engineered and capable of human speech, who eloquently describes the horrors the company has inflicted.
Fleeing the building in a madcap chase set to The Monkees' "Pleasant Valley Sunday", Mr. Cow reveals McBurgertown's practices and the bad health effects of its food to the media.
[1][3] Series regulars Peter Shin and James Purdun acted as supervising directors for the episode.
[1] This is one of the episodes of Family Guy that was released after the show's creator, Seth MacFarlane, joined the Writers Guild of America strike.
[4] In addition to the regular cast, actors Camille Guaty, Denis Martel, Ted McGinley and Ricardo Montalbán guest starred in the episode (Montalbán would one year later guest star in the episode "Moon Over Isla Island" on MacFarlane's other show, American Dad).
[6] There is a musical chase sequence through multiple doors and a hallway, inspired by late 1960s Saturday morning cartoons like The Archies and Scooby-Doo, backed by the 1967 song "Pleasant Valley Sunday" by The Monkees.
[4][6] J. Wellington Wimpy (from the comic strip Popeye) makes a cameo appearance (as an in-gag to both his drooping facial features and affinity for hamburgers).