Me, Myself & Irene is a 2000 American slapstick romantic black comedy film[2] directed by the Farrelly brothers, and starring Jim Carrey and Renée Zellweger.

Chris Cooper, Robert Forster, Richard Jenkins, Daniel Greene, Anthony Anderson, Jerod Mixon and Mongo Brownlee co-star.

The film is about a Rhode Island state trooper named Charlie who, after years of continuously suppressing his rage and feelings, suffers a psychotic breakdown that results in a second personality, Hank.

[3][4][5] Meek veteran Rhode Island state trooper Charlie Baileygates has been taken advantage of by those around him, including his wife Layla.

Despite his friends warning him of Layla's infidelity, Charlie denies it, even after she gives birth to biracial triplets, Jamal, Lee Harvey, and Shonté Jr., who also appear to be geniuses.

Believing Charlie needs a vacation, his commanding officer orders him to escort beautiful Irene Waters from Rhode Island to Massena, New York, where she reportedly committed a hit-and-run.

FBI agents begin pursuing him and Irene, as do Boshane and Gerke, two crooked police officers on Dickie's payroll.

The film's original score was written by Pete Yorn, while the movie's soundtrack contains eight covers of Steely Dan songs.

* Steely Dan cover "Motherfucker" by The Dwarves, "Fire Like This" by Hardknox, "Don't Say You Don't Remember" by Beverly Bremers, "The Perpetrator" by Hipster Daddy-O and the Handgrenades, "Love Me Cha Cha" by Jimmy Luxury, "Hem of Your Garment" by Cake, and "Highway Patrol" by Junior Brown were included in the movie but not on the soundtrack.

On June 9, 2000, the National Alliance on Mental Illness (NAMI) sent a letter to 20th Century Fox, arguing that the film contains an inaccurate portrayal of Dissociative Identity Disorder.

[11] In the letter, NAMI executive president Lauire Flynn argued that "Me, Myself & Irene perpetuates a myth that schizophrenia—a severe, biologically-based brain disorder—is a split personality", and criticized how Fox was "seeking to dismiss such concerns with claims that the film is 'only a comedy'", stating that "for millions of Americans, schizophrenia and other mental illnesses are no laughing matter".