It is reported as part of a standard complete blood count.
MCH=(Hb*10)/RBC (in millions)[3] A normal MCH value in humans is 27 to 33 picograms (pg)/cell.
[4] The mass of the red cell is determined by the iron (as part of the hemoglobin molecule), thus MCH in picograms is roughly the mass of one red cell.
The MCH decreases when Hb synthesis is reduced, or when RBCs are smaller than normal, such as in cases of iron-deficiency anemia.
[1] Conversion to SI-units: 1 pg of hemoglobin = 0.06207 femtomole (fmol).