As a teen, she took voice lessons in her home town, and spent summers on scholarships at the Boston Conservatory and at a choral camp in Rothesay, New Brunswick.

[4] At age 20, Brueggergosman played the lead in the premiere of the opera Beatrice Chancy by James Rolfe and George Elliott Clarke.

She has also performed the Verdi Requiem with Sir Andrew Davis and the Toronto Symphony Orchestra, as well as with Helmuth Rilling at the International Beethoven Festival in Bonn.

In 2002, she was the soprano soloist in the Canadian premiere of Krzysztof Penderecki's Credo, under the direction of its composer, and in the attendance of the then Governor General of Canada, Adrienne Clarkson.

In 2005, Brueggergosman was a soloist in recording William Bolcom's Songs of Innocence and Experience, which won three Grammy Awards, including Best Classical Album.

[3] In July 2007 she was a new performer at the Royal Nova Scotia International Tattoo, singing in the 'Phantom of the Opera' medley and closing the show with "Ave Maria".

In 2021 she created the symphonic short film Forgotten Coast, an exploration of Black Canadian history in Nova Scotia, for the National Arts Centre/CBC Gem series Undisrupted.

[7] In 2007, Brueggergosman became the Goodwill Ambassador for the African Medical & Research Foundation (AMREF), a charity working for Better Health in Africa.

[8] In June of that year she travelled to the war-affected village of Patongo in East Africa to share her voice as a form of musical therapy for children.

The recipient of the prestigious Canada Council and Chalmers Performing Arts grants, Brueggergosman has been twice nominated for Juno Awards.

She won the 2008 Juno Award for Classical Album of the Year: Vocal or Choral Performance for Surprise, recorded with Deutsche Grammophon, with whom she has an exclusive contract.

In 2015, she appeared in the documentary television series Songs of Freedom, which profiled her exploring and learning about her African heritage leading up to a live concert performance of African-American spiritual music.