[3]: 220 [1] This measure was created in 2003 by the Health Action International (HAI) and World Health Organization (WHO) as a standard measure to facilitate national and international comparisons of drug prices.
[1]: 41 In the WHO/HAI systematic methodology, the same provider of international reference unit price "must be used for all medicines surveyed – global, regional and supplementary", to ensure a consistent basis for comparison.
[1]: 38 Some authors criticized the MPR, as it can be skewed by the international reference price.
[4] To solve this issue, the WHO/HAI recommend to check the international reference price when very high or low MPR variations are observed.
[6] The HAI maintains a regularly updated database of worldwide MPR surveys.