MCW is accredited by the Higher Learning Commission of the North Central Association of Colleges and Schools (HLC) and by the Liaison Committee on Medical Education (LCME).

[5] During World War II, the school developed close ties with the local Veterans Health Administration hospital in Milwaukee.

[5] Dr. Joseph Kerschner stepped down as dean, provost, and executive vice president of the School of Medicine in 2024.

[2] MCW opened a new campus in Green Bay in July 2015 that provides a focused, three-year curriculum for students seeking careers in primary care, general surgery, or psychiatry.

Subjective factors include applicant's personal statement, essays, experiences, recommendations, and interviews.

[22] MCW is the largest research center in the Milwaukee metropolitan area and the second-largest in Wisconsin.

During this timeframe, the institution ranked in the top third of all US medical schools in NIH research support.