[1] Produced by the band's vocalist Oliver Sykes and keyboardist Jordan Fish, it is featured on the group's 2019 sixth studio album Amo.

[8] It has aggressive and directly angry lyrics, contrasting with romantic love songs like "Mother Tongue".

[9] While Sykes has explained that the song "Ouch" also talks about that situation, keyboardist Jordan Fish revealed that "Medicine" is "connected to that too."

Fish said of the song's lyrics: "It's about people who are negative influences and how when they leave your life things get much better.

According to music website Consequence of Sound, the video shows "a statue-like bust of singer Oli Sykes' head as it is engorged by a plague of demon-like representations of himself".