The editor-in-chief is Allister Vale (City Hospital, Birmingham).

The journal aims to cover the fundamentals of internal medicine in a systematic way during a recurring four-year cycle – it can be seen as a general medicine textbook that is published "a chapter at a time".

It covers the topics at a level appropriate to the non-specialist, providing clinicians with up-to-date, understandable clinical information.

It is aimed specifically at trainees in internal medicine and its specialties who are preparing for postgraduate examinations.

The journal is abstracted and indexed by Scopus[1] and Embase.