MECD is characterized by the formation of microcysts in the outermost layer of the cornea, known as the anterior corneal epithelium.

[3] Meesmann corneal dystrophy is a non-inflammatory condition that effects the restricted region of the cornea epithelium which is the outermost layer.

[2] Patients with Meesmann corneal dystrophy may remain asymptomatic or experience mild symptoms.

Symptoms of Meesmann corneal dystrophy often go unnoticed and is usually found and diagnosed during routine eye examinations.

[13] This slowly progressive disorder is characterized by microcysts that are filled with debris in the epithelium of the cornea detected and clinically diagnosed with slit-lamp biomicroscopy and retroillumination.

Under slit-lamp photography, the cornea was found to be uneven due to the damage and scarring from the thickening basement membrane and anterior stroma.

[1] Currently there are researchers studying the use of allele-specific siRNA against mutants with single-nucleotide specificity as a potential method of treatment for MECD.