Gelatinous drop-like corneal dystrophy

[1] The main pathological features in this dystrophy are mulberry-shaped gelatinous masses beneath the corneal epithelium.

Patients suffer from photophobia, foreign body sensation in the cornea.

[2] This form of corneal amyloidosis appears to be more frequent in Japan.

[3] A number of mutations causing this disease have been described in the M1S1 (TACSTD2) gene encoding Tumor-associated calcium signal transducer 2, but not all patients have these mutations, suggesting involvement of other genes.

[4] Media related to Gelatinous drop-like corneal dystrophy at Wikimedia Commons

Apple green dichroism of subepithelial deposition of amyloid viewed under polarized light. Congo red stain.